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Saints make four changes to the side that went down bravely at Spurs a couple of weeks ago. Alex McCarthy replaces Angus Gunn in goal. Kyle Walker-Peters makes his debut at right back. Jannik Vestergaard and Stuart Armstrong return. Missing out: Jan Bednarek, Oriol Romeu and Nathan Redmond.
Burnley make just the one change to the XI named for the goalless draw with Arsenal. Matt Lowton is replaced by Phil Bardsley.
Southampton: McCarthy, Walker-Peters, Stephens, Vestergaard, Bertrand, Armstrong, Ward-Prowse, Hojbjerg, Boufal, Long, Ings.
Subs: Adams, Djenepo, Romeu, Obafemi, Smallbone, Gunn, Bednarek.
Burnley: Pope, Bardsley, Tarkowski, Mee, Taylor, Hendrick, Westwood, Cork, McNeil, Rodriguez, Wood.
Subs: Brownhill, Brady, Hart, Pieters, Lennon, Vydra, Long.